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KMID : 1155520190140030335
Anesthesia and Pain Medicine
2019 Volume.14 No. 3 p.335 ~ p.340
Multiple epidural fibrin glue patches in a patient with spontaneous intracranial hypotension - A case report -
Lee Yun-Gu

Sa Mi-Jung
Oh In-Su
Lim Jeong-Ae
Woo Nam-Sik
Kim Jae-Hun
Abstract
Background: Spontaneous intracranial hypotension (SIH) is a condition caused by spontaneous leakage of cerebrospinal fluid, with postural headache as the primary symptom. Orthostatic headache caused by SIH is often not resolved by conservative management.

Case: We performed 15 epidural blood patch treatments in a 43-year-old female patient; however, they were only transiently effective. To improve the patient¡¯s SIH and orthostatic headache, epidural fibrin glue patch treatment was attempted. Fibrin glue is a substance that can act as a bio-friendly adhesive by facilitating the coagulation cascade. In our case, 3 epidural fibrin glue patch treatments were performed and the symptoms completely resolved.

Conclusions: The epidural fibrin glue patch may be beneficial for the treatment of refractory postural headaches caused by SIH.
KEYWORD
Epidural blood patch, Fibrin tissue adhesive, Headache, Intracranial hypotension
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